Deadly UPS Cargo Plane Crash in Louisville: 7 Killed, 11 Injured as MD-11 Erupts in Flames During Takeoff

Nov 05, 2025 10:06 am CST

A UPS cargo plane crashed and exploded during takeoff from Louisville Muhammad Ali International Airport, killing seven people and injuring eleven others. The McDonnell Douglas MD-11 bound for Honolulu experienced an engine fire before crashing near the UPS Worldport facility, impacting nearby businesses and forcing the airport's closure. Authorities continue to investigate the violent crash that witnesses described as resembling "a war zone."